2. Gene
  3. Prickle1 - prickle planar cell polarity protein 1 Gene

Prickle1 - prickle planar cell polarity protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Rilp

Gene ID: 315259 | Gene type: protein coding

About Prickle1

Summary

Predicted to enable zinc ion binding activity. Involved in protein import into nucleus. Predicted to be located in cytosol and nuclear membrane. Used to study temporal lobe epilepsy. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Orthologous to human PRICKLE1 (prickle planar cell polarity protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Prickle1 Products(1)

mRNA Protein Name
NM_199396.1 NP_955428.1 prickle-like protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
14645515 RGD
Biological Process GO Annotation Evidence Reference Source
involved in protein import into nucleus IDA
IDA: Inferred from direct assay
14645515 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prickle-like protein 1

REST/NRSF-interacting LIM domain protein 1

prickle homolog 1

prickle-like 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11093 PRICKLE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prickle1 NCBI NCBI:144165