Ocrl - OCRL, inositol polyphosphate-5-phosphatase Gene

Also Known as OCRL-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 317576

Summary

Predicted to enable GTPase activator activity; Phosphatase activity; and small GTPase binding activity. Predicted to be involved in cilium assembly; dephosphorylation; and regulation of GTPase activity. Predicted to act upstream of or within in utero embryonic development. Predicted to be located in several cellular components, including cytoplasmic vesicle; photoreceptor outer segment; and trans-Golgi network. Predicted to be active in cytoplasm and membrane. Human ortholog(s) of this gene implicated in Dent disease and oculocerebrorenal syndrome. Orthologous to human OCRL (OCRL inositol polyphosphate-5-phosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Ocrl Products (1)

mRNA Protein Name
NM_001108256.2 NP_001101726.2 inositol polyphosphate 5-phosphatase OCRL

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19795375 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inositol polyphosphate 5-phosphatase OCRL

  • inositol polyphosphate 5-phosphatase OCRL-1

  • oculocerebrorenal syndrome of Lowe

  • phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-120354 YU142670 Inhibitor 99.50% Unkown
HY-117087 K103 Inducer / Unkown
HY-RS09746 OCRL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ocrl NCBI NCBI:4952