2. Gene
  3. Ocrl - OCRL, inositol polyphosphate-5-phosphatase Gene

Ocrl - OCRL, inositol polyphosphate-5-phosphatase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as OCRL-1

Gene ID: 317576 | Gene type: protein coding

About Ocrl

Summary

Predicted to enable GTPase activator activity; Phosphatase activity; and small GTPase binding activity. Predicted to be involved in cilium assembly; dephosphorylation; and regulation of GTPase activity. Predicted to act upstream of or within in utero embryonic development. Predicted to be located in several cellular components, including cytoplasmic vesicle; photoreceptor outer segment; and trans-Golgi network. Predicted to be active in cytoplasm and membrane. Human ortholog(s) of this gene implicated in Dent disease and oculocerebrorenal syndrome. Orthologous to human OCRL (OCRL inositol polyphosphate-5-phosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Ocrl Products(1)

mRNA Protein Name
NM_001108256.2 NP_001101726.2 inositol polyphosphate 5-phosphatase OCRL
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19795375 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inositol polyphosphate 5-phosphatase OCRL

inositol polyphosphate 5-phosphatase OCRL-1

oculocerebrorenal syndrome of Lowe

phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120354 YU142670 Inhibitor 99.50% Unkown
HY-117087 K103 Inducer / Unkown
HY-RS09746 OCRL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ocrl NCBI NCBI:4952