2. Gene
  3. HNRNPH3 - heterogeneous nuclear ribonucleoprotein H3 Gene

HNRNPH3 - heterogeneous nuclear ribonucleoprotein H3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as 2H9; HNRPH3

Gene ID: 3189 | Gene type: protein coding

About HNRNPH3

Cytogenetic location: 10q21.3 Genomic coordinates (GRCh38): 10:68,331,693-68,343,196 (from NCBI)

This gene has 11 transcripts (splice variants), 219 orthologues and 8 paralogues. Ubiquitous expression in endometrium (RPKM 44.3), ovary (RPKM 43.6) and 25 other tissues.

Summary

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008]

HNRNPH3 Products(21)

mRNA Protein Name
NM_001322434.2 NP_001309363.1 heterogeneous nuclear ribonucleoprotein H3 isoform a
NM_001322436.2 NP_001309365.1 heterogeneous nuclear ribonucleoprotein H3 isoform a
NM_001322437.2 NP_001309366.1 heterogeneous nuclear ribonucleoprotein H3 isoform a
NM_001322438.1 NP_001309367.1 heterogeneous nuclear ribonucleoprotein H3 isoform b
NM_001322439.2 NP_001309368.1 heterogeneous nuclear ribonucleoprotein H3 isoform b
NM_001322440.2 NP_001309369.1 heterogeneous nuclear ribonucleoprotein H3 isoform b
NM_001322441.2 NP_001309370.1 heterogeneous nuclear ribonucleoprotein H3 isoform b
NM_001322442.2 NP_001309371.1 heterogeneous nuclear ribonucleoprotein H3 isoform c
NM_001322443.2 NP_001309372.1 heterogeneous nuclear ribonucleoprotein H3 isoform c
NM_001322444.2 NP_001309373.1 heterogeneous nuclear ribonucleoprotein H3 isoform d
NM_001322445.1 NP_001309374.1 heterogeneous nuclear ribonucleoprotein H3 isoform e
NM_001322446.2 NP_001309375.1 heterogeneous nuclear ribonucleoprotein H3 isoform e
NM_001322447.2 NP_001309376.1 heterogeneous nuclear ribonucleoprotein H3 isoform e
NM_001322448.2 NP_001309377.1 heterogeneous nuclear ribonucleoprotein H3 isoform e
NM_001322449.2 NP_001309378.1 heterogeneous nuclear ribonucleoprotein H3 isoform e
NM_001322450.2 NP_001309379.1 heterogeneous nuclear ribonucleoprotein H3 isoform f
NM_001322451.2 NP_001309380.1 heterogeneous nuclear ribonucleoprotein H3 isoform g
NM_001322452.2 NP_001309381.1 heterogeneous nuclear ribonucleoprotein H3 isoform g
NM_001322453.2 NP_001309382.1 heterogeneous nuclear ribonucleoprotein H3 isoform g
NM_012207.3 NP_036339.1 heterogeneous nuclear ribonucleoprotein H3 isoform a
NM_021644.4 NP_067676.2 heterogeneous nuclear ribonucleoprotein H3 isoform b

HNRNPH3 Protein Structure

(18 - 87)

(197 - 264)

  • 0
  • 100
  • 200
  • 300
  • 346 a.a.
Protein Preferred Names Protein Names

heterogeneous nuclear ribonucleoprotein H3

heterogeneous nuclear ribonucleoprotein 2H9

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06272 HNRNPH3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris HNRNPH3 VGNC VGNC:41732
Mus musculus HNRNPH3 MGD MGI:1926462
Macaca mulatta HNRNPH3 VGNC VGNC:73497
Bos taurus HNRNPH3 VGNC VGNC:29896
Rattus norvegicus HNRNPH3 RGD RGD:1310019