Spx - spexin hormone Gene

Also Known as Npq; B230216G23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 319552

Summary

Predicted to enable neuropeptide hormone activity; type 2 Galanin receptor binding activity; and type 3 Galanin receptor binding activity. Involved in long-chain fatty acid import into cell and negative regulation of appetite. Predicted to be located in dense core granule. Predicted to be active in cytoplasm and extracellular space. Is expressed in esophagus and stomach fundus submucosa. Orthologous to human SPX (spexin hormone). [provided by Alliance of Genome Resources, Apr 2022]

Spx Products (2)

mRNA Protein Name
NM_001242345.1 NP_001229274.1 spexin isoform 1 precursor
NM_001369015.1 NP_001355944.1 spexin isoform 2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in long-chain fatty acid import into cell IDA
IDA: Inferred from direct assay
24550067 MGI
involved in negative regulation of appetite IDA
IDA: Inferred from direct assay
24550067 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spexin

  • neuropeptide Q

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P5931 Spinoxin Inhibitor 98.0% Phase 1

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13741 SPX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992508 SPX-101 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spx NCBI NCBI:80763