2. Gene
  3. Spx - spexin hormone Gene

Spx - spexin hormone Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Npq; B230216G23Rik

Gene ID: 319552 | Gene type: protein coding

About Spx

Summary

Predicted to enable neuropeptide hormone activity; type 2 Galanin receptor binding activity; and type 3 Galanin receptor binding activity. Involved in long-chain fatty acid import into cell and negative regulation of appetite. Predicted to be located in dense core granule. Predicted to be active in cytoplasm and extracellular space. Is expressed in esophagus and stomach fundus submucosa. Orthologous to human SPX (spexin hormone). [provided by Alliance of Genome Resources, Apr 2022]

Spx Products(2)

mRNA Protein Name
NM_001242345.1 NP_001229274.1 spexin isoform 1 precursor
NM_001369015.1 NP_001355944.1 spexin isoform 2 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in long-chain fatty acid import into cell IDA
IDA: Inferred from direct assay
24550067 MGI
involved in negative regulation of appetite IDA
IDA: Inferred from direct assay
24550067 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spexin

neuropeptide Q

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P5931 Spinoxin Inhibitor 98.0% Phase 1
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13741 SPX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P992508 SPX-101 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spx NCBI NCBI:80763