2. Gene
  3. Zfyve27 - zinc finger, FYVE domain containing 27 Gene

Zfyve27 - zinc finger, FYVE domain containing 27 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2210011N02Rik; 9530077C24Rik

Gene ID: 319740 | Gene type: protein coding

About Zfyve27

Summary

Predicted to enable identical protein binding activity and protein self-association. Involved in positive regulation of axon extension and vesicle-mediated transport. Located in dendrite; endoplasmic reticulum tubular network; and growth cone membrane. Is integral component of membrane. Is expressed in ganglia; genitourinary system; sensory organ; and vibrissa. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 33. Orthologous to human ZFYVE27 (zinc finger FYVE-type containing 27). [provided by Alliance of Genome Resources, Apr 2022]

Zfyve27 Products(2)

mRNA Protein Name
NM_001164531.1 NP_001158003.1 protrudin isoform 2
NM_177319.3 NP_796293.2 protrudin isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21976701 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of axon extension IMP
IMP: Inferred from mutant phenotype
24251978 MGI
involved in vesicle-mediated transport IDA
IDA: Inferred from direct assay
21976701 MGI
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
17082457 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
17082457 MGI
located in dendrite IDA
IDA: Inferred from direct assay
17082457 MGI
located in endoplasmic reticulum tubular network IDA
IDA: Inferred from direct assay
24668814 MGI
located in growth cone membrane IDA
IDA: Inferred from direct assay
17082457 MGI
located in membrane IDA
IDA: Inferred from direct assay
24668814 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protrudin

zinc finger FYVE domain-containing protein 27

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16060 ZFYVE27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zfyve27 NCBI NCBI:118813