Ano4 - anoctamin 4 Gene

Also Known as Gm65; Tmem16d; A330096O15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320091

Summary

Enables phospholipid scramblase activity. Acts upstream of or within calcium activated galactosylceramide scrambling; calcium activated phosphatidylcholine scrambling; and calcium activated phosphatidylserine scrambling. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in dorsal root ganglion and trigeminal ganglion. Orthologous to human ANO4 (anoctamin 4). [provided by Alliance of Genome Resources, Apr 2022]

Ano4 Products (1)

mRNA Protein Name
NM_001277188.1 NP_001264117.1 anoctamin-4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
NOT enables intracellularly calcium-gated chloride channel activity IDA
IDA: Inferred from direct assay
22075693 MGI
enables phospholipid scramblase activity IDA
IDA: Inferred from direct assay
23532839 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within calcium activated galactosylceramide scrambling IDA
IDA: Inferred from direct assay
23532839 MGI
acts upstream of or within calcium activated phosphatidylcholine scrambling IDA
IDA: Inferred from direct assay
23532839 MGI
acts upstream of or within calcium activated phosphatidylserine scrambling IDA
IDA: Inferred from direct assay
23532839 MGI
acts upstream of or within establishment of localization in cell IDA
IDA: Inferred from direct assay
23532839 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

anoctamin-4

  • transmembrane protein 16D (eight membrane-spanning domains)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00744 ANO4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ano4 NCBI NCBI:121601