2. Gene
  3. Ttll5 - tubulin tyrosine ligase-like family, member 5 Gene

Ttll5 - tubulin tyrosine ligase-like family, member 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Stamp; mKIAA0998; 1700048H13Rik; 2310009M18Rik; 4930556H18Rik; D630041K24Rik

Gene ID: 320244 | Gene type: protein coding

About Ttll5

Summary

Predicted to enable tubulin binding activity and tubulin-glutamic acid Ligase activity. Acts upstream of or within fertilization; protein polyglutamylation; and sperm axoneme assembly. Located in 9+0 non-motile cilium and ciliary basal body. Is expressed in choroid invagination; diencephalon roof plate; medulla oblongata part of 4th ventricle choroid plexus; and metencephalon part of 4th ventricle choroid plexus. Human ortholog(s) of this gene implicated in cone-rod dystrophy 19. Orthologous to human TTLL5 (tubulin tyrosine Ligase like 5). [provided by Alliance of Genome Resources, Apr 2022]

Ttll5 Products(8)

mRNA Protein Name
NM_001081423.3 NP_001074892.2 tubulin polyglutamylase TTLL5 isoform 1
NM_001347395.2 NP_001334324.1 tubulin polyglutamylase TTLL5 isoform 2
NM_001364624.1 NP_001351553.1 tubulin polyglutamylase TTLL5 isoform 3
NM_001364625.1 NP_001351554.1 tubulin polyglutamylase TTLL5 isoform 4
NM_001364626.1 NP_001351555.1 tubulin polyglutamylase TTLL5 isoform 5
NM_001364627.1 NP_001351556.1 tubulin polyglutamylase TTLL5 isoform 6
NM_001364628.1 NP_001351557.1 tubulin polyglutamylase TTLL5 isoform 7
NM_001364630.1 NP_001351559.1 tubulin polyglutamylase TTLL5 isoform 8
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables tubulin-glutamic acid ligase activity IDA
IDA: Inferred from direct assay
17499049 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within fertilization IMP
IMP: Inferred from mutant phenotype
23558686 MGI
acts upstream of or within flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
23558686 MGI
acts upstream of or within protein polyglutamylation IMP
IMP: Inferred from mutant phenotype
23558686 MGI
acts upstream of or within sperm axoneme assembly IMP
IMP: Inferred from mutant phenotype
23558686 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
23558686 MGI
Cellular Component GO Annotation Evidence Reference Source
located in 9+0 non-motile cilium IDA
IDA: Inferred from direct assay
17499049 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
17499049 MGI
located in cilium IDA
IDA: Inferred from direct assay
24791901 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin polyglutamylase TTLL5

polyglutamylase

tubulin tyrosine ligase like family 5

tubulin--tyrosine ligase-like protein 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15232 TTLL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttll5 NCBI NCBI:23093