Abi3bp - ABI family member 3 binding protein Gene
Also Known as TARSH; eratin; 5033411B22Rik; D930038M13Rik
Species: Mus musculus
Summary
Enables Collagen binding activity and heparin binding activity. Involved in negative regulation of cell population proliferation; negative regulation of connective tissue replacement involved in inflammatory response wound healing; and positive regulation of cardiocyte differentiation. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in interstitial matrix. Is expressed in several structures, including connective tissue; gut; male reproductive gland or organ; olfactory epithelium; and quadriceps femoris muscle. Orthologous to human ABI3BP (ABI family member 3 binding protein). [provided by Alliance of Genome Resources, Apr 2022]
Abi3bp Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_001014399.2 | NP_001014421.2 | target of Nesh-SH3 isoform 3 precursor |
| NM_001014422.2 | NP_001014422.1 | target of Nesh-SH3 isoform 4 precursor |
| NM_001014423.2 | NP_001014423.1 | target of Nesh-SH3 isoform 5 precursor |
| NM_001014424.2 | NP_001014424.1 | target of Nesh-SH3 isoform 2 precursor |
| NM_178790.4 | NP_848905.2 | target of Nesh-SH3 isoform 1 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables collagen binding |
IDA
IDA: Inferred from direct assay
|
18757743 | MGI |
| enables glycosaminoglycan binding |
IDA
IDA: Inferred from direct assay
|
18757743 | MGI |
| enables heparin binding |
IDA
IDA: Inferred from direct assay
|
18757743 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within extracellular matrix organization |
IDA
IDA: Inferred from direct assay
|
18757743 | MGI |
| acts upstream of or within positive regulation of cell-substrate adhesion |
IDA
IDA: Inferred from direct assay
|
18757743 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in extracellular matrix |
IDA
IDA: Inferred from direct assay
|
18757743 | MGI |
| located in interstitial matrix |
IDA
IDA: Inferred from direct assay
|
18757743 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
target of Nesh-SH3 |
|