Atp11c - ATPase, class VI, type 11C Gene

Also Known as Ig; A330005H02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320940

Summary

Predicted to enable phosphatidylethanolamine flippase activity and phosphatidylserine flippase activity. Involved in phospholipid translocation; positive regulation of B cell differentiation; and pre-B cell differentiation. Predicted to be integral component of plasma membrane. Predicted to be active in several cellular components, including endoplasmic reticulum; recycling endosome; and trans-Golgi network. Is expressed in choroid invagination; diencephalon roof plate; and metencephalon part of 4th ventricle choroid plexus. Human ortholog(s) of this gene implicated in X-linked congenital hemolytic anemia. Orthologous to human ATP11C (ATPase phospholipid transporting 11C). [provided by Alliance of Genome Resources, Apr 2022]

Atp11c Products (3)

mRNA Protein Name
NM_001001798.3 NP_001001798.1 phospholipid-transporting ATPase 11C isoform b
NM_001037863.2 NP_001032952.1 phospholipid-transporting ATPase 11C isoform a
NM_001359002.1 NP_001345931.1 phospholipid-transporting ATPase 11C isoform c

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in phospholipid translocation IMP
IMP: Inferred from mutant phenotype
21423173 MGI
involved in positive regulation of B cell differentiation IMP
IMP: Inferred from mutant phenotype
21423173 MGI
involved in pre-B cell differentiation IMP
IMP: Inferred from mutant phenotype
21423173 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipid-transporting ATPase 11C

  • Atpase 11c, p type

  • P4-ATPase flippase complex alpha subunit ATP11C

  • probable phospholipid-transporting ATPase 11C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01176 ATP11C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp11c NCBI NCBI:286410