2. Gene
  3. Atp11c - ATPase, class VI, type 11C Gene

Atp11c - ATPase, class VI, type 11C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ig; A330005H02Rik

Gene ID: 320940 | Gene type: protein coding

About Atp11c

Summary

Predicted to enable phosphatidylethanolamine flippase activity and phosphatidylserine flippase activity. Involved in phospholipid translocation; positive regulation of B cell differentiation; and pre-B cell differentiation. Predicted to be integral component of plasma membrane. Predicted to be active in several cellular components, including endoplasmic reticulum; recycling endosome; and trans-Golgi network. Is expressed in choroid invagination; diencephalon roof plate; and metencephalon part of 4th ventricle choroid plexus. Human ortholog(s) of this gene implicated in X-linked congenital hemolytic anemia. Orthologous to human ATP11C (ATPase phospholipid transporting 11C). [provided by Alliance of Genome Resources, Apr 2022]

Atp11c Products(3)

mRNA Protein Name
NM_001001798.3 NP_001001798.1 phospholipid-transporting ATPase 11C isoform b
NM_001037863.2 NP_001032952.1 phospholipid-transporting ATPase 11C isoform a
NM_001359002.1 NP_001345931.1 phospholipid-transporting ATPase 11C isoform c
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in phospholipid translocation IMP
IMP: Inferred from mutant phenotype
21423173 MGI
involved in positive regulation of B cell differentiation IMP
IMP: Inferred from mutant phenotype
21423173 MGI
involved in pre-B cell differentiation IMP
IMP: Inferred from mutant phenotype
21423173 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipid-transporting ATPase 11C

Atpase 11c, p type

P4-ATPase flippase complex alpha subunit ATP11C

probable phospholipid-transporting ATPase 11C

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01176 ATP11C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp11c NCBI NCBI:286410