Upf2 - UPF2 regulator of nonsense transcripts homolog (yeast) Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 326622

Summary

Predicted to enable telomeric DNA binding activity. Acts upstream of or within animal organ regeneration and liver development. Predicted to be located in several cellular components, including cytoplasmic ribonucleoprotein granule; cytosol; and perinuclear region of cytoplasm. Predicted to be part of exon-exon junction complex and polysome. Predicted to be active in cytoplasm. Is expressed in several structures, including heart; liver; lung; spleen; and testis. Orthologous to human UPF2 (UPF2 regulator of nonsense mediated mRNA decay). [provided by Alliance of Genome Resources, Apr 2022]

Upf2 Products (1)

mRNA Protein Name
NM_001081132.1 NP_001074601.1 regulator of nonsense transcripts 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within animal organ regeneration IMP
IMP: Inferred from mutant phenotype
20657840 MGI
acts upstream of or within liver development IMP
IMP: Inferred from mutant phenotype
20657840 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

regulator of nonsense transcripts 2

  • nonsense mRNA reducing factor 2

  • up-frameshift suppressor 2 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15483 UPF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Upf2 NCBI NCBI:26019