Med13 - mediator complex subunit 13 Gene

Also Known as Thrap1; Trap240; D030023K18; 1110067M05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 327987

Summary

Predicted to enable Thyroid Hormone Receptor binding activity and transcription coactivator activity. Involved in Cholesterol homeostasis; negative regulation of DNA-binding transcription factor activity; and triglyceride homeostasis. Part of mediator complex. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human MED13 (mediator complex subunit 13). [provided by Alliance of Genome Resources, Apr 2022]

Med13 Products (1)

mRNA Protein Name
NM_001080931.2 NP_001074400.1 mediator of RNA polymerase II transcription subunit 13

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cholesterol homeostasis IDA
IDA: Inferred from direct assay
22541436 MGI
involved in negative regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
22541436 MGI
involved in triglyceride homeostasis IDA
IDA: Inferred from direct assay
22541436 MGI
Cellular Component GO Annotation Evidence References Source
part of mediator complex IDA
IDA: Inferred from direct assay
15340084 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 13

  • Zmediator complex subunit 13

  • mediator of RNA polymerase II transcription, subunit 13

  • thyroid hormone receptor associated protein 1

  • thyroid hormone receptor associated protein, 240 kDa subunit

  • thyroid hormone receptor-associated protein complex 240 kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08283 MED13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08284 MED13L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Med13 NCBI NCBI:9969