2. Gene
  3. Med13 - mediator complex subunit 13 Gene

Med13 - mediator complex subunit 13 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Thrap1; Trap240; D030023K18; 1110067M05Rik

Gene ID: 327987 | Gene type: protein coding

About Med13

Summary

Predicted to enable Thyroid Hormone Receptor binding activity and transcription coactivator activity. Involved in Cholesterol homeostasis; negative regulation of DNA-binding transcription factor activity; and triglyceride homeostasis. Part of mediator complex. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human MED13 (mediator complex subunit 13). [provided by Alliance of Genome Resources, Apr 2022]

Med13 Products(1)

mRNA Protein Name
NM_001080931.2 NP_001074400.1 mediator of RNA polymerase II transcription subunit 13
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cholesterol homeostasis IDA
IDA: Inferred from direct assay
22541436 MGI
involved in negative regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
22541436 MGI
involved in triglyceride homeostasis IDA
IDA: Inferred from direct assay
22541436 MGI
Cellular Component GO Annotation Evidence Reference Source
part of mediator complex IDA
IDA: Inferred from direct assay
15340084 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 13

Zmediator complex subunit 13

mediator of RNA polymerase II transcription, subunit 13

thyroid hormone receptor associated protein 1

thyroid hormone receptor associated protein, 240 kDa subunit

thyroid hormone receptor-associated protein complex 240 kDa

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08283 MED13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08284 MED13L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Med13 NCBI NCBI:9969