Fat4 - FAT atypical cadherin 4 Gene

Predicted to enable calcium ion binding activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; hippo signaling; and nervous system development. Acts upstream of or within several processes, including animal organ development; cell surface receptor signaling pathway; and condensed mesenchymal cell proliferation. Located in apical part of cell. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system gland; lung; and metanephros. Human ortholog(s) of this gene implicated in Hennekam syndrome and Van Maldergem syndrome 2. Orthologous to human FAT4 (FAT atypical Cadherin 4). [provided by Alliance of Genome Resources, Apr 2022]