2. Gene
  3. Kctd10 - potassium channel tetramerisation domain containing 10 Gene

Kctd10 - potassium channel tetramerisation domain containing 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mBACURD3

Gene ID: 330171 | Gene type: protein coding

About Kctd10

Summary

Predicted to enable Notch binding activity and identical protein binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Acts upstream of or within angiogenesis; heart development; and negative regulation of Notch signaling pathway. Part of MKS complex. Is expressed in clavicle; mandible; maxilla; midgut; and rib. Orthologous to human KCTD10 (Potassium Channel tetramerization domain containing 10). [provided by Alliance of Genome Resources, Apr 2022]

Kctd10 Products(2)

mRNA Protein Name
NM_001159941.1 NP_001153413.1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform 1
NM_026145.4 NP_080421.2 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22179047 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within angiogenesis IMP
IMP: Inferred from mutant phenotype
25401743 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
25401743 MGI
acts upstream of or within negative regulation of Notch signaling pathway IMP
IMP: Inferred from mutant phenotype
25401743 MGI
Cellular Component GO Annotation Evidence Reference Source
part of MKS complex IDA
IDA: Inferred from direct assay
22179047 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

BTB/POZ domain-containing protein KCTD10

potassium channel tetramerization domain-containing 10

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07187 KCTD10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kctd10 NCBI NCBI:83892