Arhgap32 - Rho GTPase activating protein 32 Gene

Also Known as Grit; Rics; Gc-gap; Px-rics; p250Gap; mKIAA0712; p200Rhogap; 3426406O18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 330914

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in small GTPase mediated signal transduction. Predicted to act upstream of or within Rho protein signal transduction. Located in actin cytoskeleton; cell cortex; and postsynaptic density. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Used to study autism spectrum disorder. Orthologous to human ARHGAP32 (Rho GTPase activating protein 32). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap32 Products (4)

mRNA Protein Name
NM_001195632.2 NP_001182561.1 rho GTPase-activating protein 32 isoform 1
NM_001370957.1 NP_001357886.1 rho GTPase-activating protein 32 isoform 4
NM_001370958.1 NP_001357887.1 rho GTPase-activating protein 32 isoform 3
NM_177379.5 NP_796353.3 rho GTPase-activating protein 32 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27609886 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
12454018 MGI
located in cell cortex IDA
IDA: Inferred from direct assay
12454018 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
27609886 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 32

  • GAB-associated Cdc42/Rac GTPase-activating protein

  • GTPase-activating protein for Cdc42 and Rac1

  • Rho GTPase activating protein 33 pseudogene

  • brain-specific Rho GTPase-activating protein

  • rac GTPase activating protein

  • rho-type GTPase-activating protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00931 ARHGAP32 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap32 NCBI NCBI:9743