2. Gene
  3. Kcnk18 - potassium channel, subfamily K, member 18 Gene

Kcnk18 - potassium channel, subfamily K, member 18 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Trik; Gm781; Tresk; Tresk-2

Gene ID: 332396 | Gene type: protein coding

About Kcnk18

Summary

Enables calcium-activated Potassium Channel activity. Acts upstream of or within potassium ion transport. Located in plasma membrane. Is expressed in gut; male reproductive gland or organ; and olfactory lobe. Human ortholog(s) of this gene implicated in migraine with aura. Orthologous to human KCNK18 (potassium two pore domain channel subfamily K member 18). [provided by Alliance of Genome Resources, Apr 2022]

Kcnk18 Products(1)

mRNA Protein Name
NM_207261.3 NP_997144.1 potassium channel subfamily K member 18
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium-activated potassium channel activity IDA
IDA: Inferred from direct assay
14981085 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18397886 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within potassium ion transport IDA
IDA: Inferred from direct assay
14981085 MGI
involved in potassium ion transport IDA
IDA: Inferred from direct assay
20006580 MGI
involved in regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation IMP
IMP: Inferred from mutant phenotype
34702947 MGI
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
20006580 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium channel subfamily K member 18

2P K ion channel TRESK

TWIK-related individual K+ channel

TWIK-related spinal cord K+ channel

two-pore-domain potassium channel TRESK

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07157 KCNK18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnk18 NCBI NCBI:338567