Frmpd4 - FERM and PDZ domain containing 4 Gene

Also Known as Gm196; PKAP1; preso; Pdzd10; Pdzk10; Preso1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 333605

Summary

Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in positive regulation of synapse structural plasticity and postsynaptic actin Cytoskeleton organization. Predicted to be located in cell projection; cytoskeleton; and synapse. Predicted to be part of protein-containing complex. Predicted to be active in dendritic spine. Is expressed in dorsal root ganglion; facial ganglion; lateral ventricle choroid plexus; metencephalon part of 4th ventricle choroid plexus; and trigeminal ganglion. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Orthologous to human FRMPD4 (FERM and PDZ domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]

Frmpd4 Products (6)

mRNA Protein Name
NM_001033330.4 NP_001028502.1 FERM and PDZ domain-containing protein 4 isoform a
NM_001290427.2 NP_001277356.1 FERM and PDZ domain-containing protein 4 isoform a
NM_001290428.1 NP_001277357.1 FERM and PDZ domain-containing protein 4 isoform b
NM_001359072.1 NP_001346001.1 FERM and PDZ domain-containing protein 4 isoform c
NM_001368936.1 NP_001355865.1 FERM and PDZ domain-containing protein 4 isoform 5
NM_001369234.1 NP_001356163.1 FERM and PDZ domain-containing protein 4 isoform d

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
22561452 MGI
is active in postsynaptic density IDA
IDA: Inferred from direct assay
22561452 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

FERM and PDZ domain-containing protein 4

  • PDZ domain-containing protein 10

  • PSD-95-interacting regulator of spine morphogenesis

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05109 FRMPD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Frmpd4 NCBI NCBI:9758