HTR1F - 5-hydroxytryptamine receptor 1F Gene

Homo sapiens

Also known as 5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F

Gene ID: 3355 | Gene type: protein coding

About HTR1F

Cytogenetic location: 3p11.2-p11.1 Genomic coordinates (GRCh38): 3:87,792,706-87,993,839 (from NCBI)

This gene has 1 transcript (splice variant), 147 orthologues and 8 paralogues. Low expression observed in reference dataset.

Summary

Enables G protein-coupled serotonin receptor activity and serotonin binding activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

HTR1F Products(4)

mRNA	Protein	Name
NM_000866.5	NP_000857.1	5-hydroxytryptamine receptor 1F
NM_001322208.2	NP_001309137.1	5-hydroxytryptamine receptor 1F
NM_001322209.2	NP_001309138.1	5-hydroxytryptamine receptor 1F
NM_001322210.2	NP_001309139.1	5-hydroxytryptamine receptor 1F

HTR1F Protein Structure

7tm_1

0
100
200
300
366 a.a.

Protein Preferred Names

Protein Names

5-hydroxytryptamine receptor 1F

5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled

Related Diseases

Diseases

Alias

Migraine With Or Without Aura 1

Migraine	Migraine With Or Without Aura, Susceptibility To, 1
Migraine Disorder	Migraine Variant
Migraines	Migraine Disorders
Mgr1	Mgau
Ma	Migraine With Or Without Aura
Classic Migraine	Common Migraine
Disorder, Migraine	Headache Migraine
Headache Migrainous	Migraine Headache
Migraine Syndrome	Headache Including Migraine
Migraine, Susceptibility To

Intracranial Vasospasm

Vasospasm, Intracranial

Tolosa-Hunt Syndrome

Painful Ophthalmoplegia	Tolosa Hunt Syndrome
Nonspecific Inflammation Of The Cavernous Sinus Or Superior Orbital Fissure	Ths
Ophthalmoplegia, Painful

Dyslexia

Migraine With Aura

Classic Migraine	Migraine With Typical Aura
Migraine Accompagnée	Complicated Migraine
Classical Migraine	Acute Migraine With Aura

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06464	HTR1F Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	HTR1F	RGD	RGD:71083
Canis familiaris	HTR1F	VGNC	VGNC:41826
Bos taurus	HTR1F	VGNC	VGNC:29995
Felis catus	HTR1F	VGNC	VGNC:67671
Mus musculus	HTR1F	MGD	MGI:99842

Name
Email *

	Sorry, but the email address you supplied was invalid.