OBSCN - Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF Gene
Also Known as RGD1305774
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 338458
Summary
Predicted to enable several functions, including cytoskeletal protein binding activity; phosphatidylinositol phosphate binding activity; and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in negative regulation of phosphatidylinositol 3-kinase signaling and protein autophosphorylation. Located in M band and Z disc. Orthologous to human OBSCN (obscurin, cytoskeletal Calmodulin and titin-interacting RhoGEF). [provided by Alliance of Genome Resources, Apr 2022]
OBSCN Products (74)
| mRNA | Protein | Name |
|---|---|---|
| XM_039087230.1 | XP_038943158.1 | obscurin isoform X12 |
| XM_039087238.1 | XP_038943166.1 | obscurin isoform X19 |
| XM_039087228.1 | XP_038943156.1 | obscurin isoform X10 |
| XM_039087225.1 | XP_038943153.1 | obscurin isoform X7 |
| XM_039087237.1 | XP_038943165.1 | obscurin isoform X18 |
| XM_039087226.1 | XP_038943154.1 | obscurin isoform X8 |
| XM_039087227.1 | XP_038943155.1 | obscurin isoform X9 |
| XM_039087229.1 | XP_038943157.1 | obscurin isoform X11 |
| XM_039087250.1 | XP_038943178.1 | obscurin isoform X30 |
| XM_039087246.1 | XP_038943174.1 | obscurin isoform X26 |
| XM_039087249.1 | XP_038943177.1 | obscurin isoform X29 |
| XM_039087245.1 | XP_038943173.1 | obscurin isoform X25 |
| XM_039087248.1 | XP_038943176.1 | obscurin isoform X28 |
| XM_039087247.1 | XP_038943175.1 | obscurin isoform X27 |
| XM_039087243.1 | XP_038943171.1 | obscurin isoform X24 |
| XM_039087221.1 | XP_038943149.1 | obscurin isoform X3 |
| XM_039087242.1 | XP_038943170.1 | obscurin isoform X23 |
| XM_039087240.1 | XP_038943168.1 | obscurin isoform X21 |
| XM_039087235.1 | XP_038943163.1 | obscurin isoform X16 |
| XM_039087234.1 | XP_038943162.1 | obscurin isoform X15 |
| XM_039087224.1 | XP_038943152.1 | obscurin isoform X6 |
| XM_039087241.1 | XP_038943169.1 | obscurin isoform X22 |
| XM_039087239.1 | XP_038943167.1 | obscurin isoform X20 |
| XM_039087231.1 | XP_038943159.1 | obscurin isoform X13 |
| XM_039087220.1 | XP_038943148.1 | obscurin isoform X2 |
| XM_039087232.1 | XP_038943160.1 | obscurin isoform X14 |
| XM_039087223.1 | XP_038943151.1 | obscurin isoform X5 |
| XM_039087222.1 | XP_038943150.1 | obscurin isoform X4 |
| XM_039087236.1 | XP_038943164.1 | obscurin isoform X17 |
| XM_039087219.1 | XP_038943147.1 | obscurin isoform X1 |
| XM_039087254.1 | XP_038943182.1 | obscurin isoform X32 |
| XM_039087257.1 | XP_038943185.1 | obscurin isoform X34 |
| XM_039087256.1 | XP_038943184.1 | obscurin isoform X33 |
| XM_039087253.1 | XP_038943181.1 | obscurin isoform X32 |
| XM_039087252.1 | XP_038943180.1 | obscurin isoform X31 |
| XM_039087251.1 | XP_038943179.1 | obscurin isoform X31 |
| XM_039087258.1 | XP_038943186.1 | obscurin isoform X35 |
| XM_039087230.1 | XP_038943158.1 | obscurin isoform X12 |
| XM_039087238.1 | XP_038943166.1 | obscurin isoform X19 |
| XM_039087228.1 | XP_038943156.1 | obscurin isoform X10 |
| XM_039087225.1 | XP_038943153.1 | obscurin isoform X7 |
| XM_039087237.1 | XP_038943165.1 | obscurin isoform X18 |
| XM_039087226.1 | XP_038943154.1 | obscurin isoform X8 |
| XM_039087227.1 | XP_038943155.1 | obscurin isoform X9 |
| XM_039087229.1 | XP_038943157.1 | obscurin isoform X11 |
| XM_039087250.1 | XP_038943178.1 | obscurin isoform X30 |
| XM_039087246.1 | XP_038943174.1 | obscurin isoform X26 |
| XM_039087249.1 | XP_038943177.1 | obscurin isoform X29 |
| XM_039087245.1 | XP_038943173.1 | obscurin isoform X25 |
| XM_039087248.1 | XP_038943176.1 | obscurin isoform X28 |
| XM_039087247.1 | XP_038943175.1 | obscurin isoform X27 |
| XM_039087243.1 | XP_038943171.1 | obscurin isoform X24 |
| XM_039087221.1 | XP_038943149.1 | obscurin isoform X3 |
| XM_039087242.1 | XP_038943170.1 | obscurin isoform X23 |
| XM_039087240.1 | XP_038943168.1 | obscurin isoform X21 |
| XM_039087235.1 | XP_038943163.1 | obscurin isoform X16 |
| XM_039087234.1 | XP_038943162.1 | obscurin isoform X15 |
| XM_039087224.1 | XP_038943152.1 | obscurin isoform X6 |
| XM_039087241.1 | XP_038943169.1 | obscurin isoform X22 |
| XM_039087239.1 | XP_038943167.1 | obscurin isoform X20 |
| XM_039087231.1 | XP_038943159.1 | obscurin isoform X13 |
| XM_039087220.1 | XP_038943148.1 | obscurin isoform X2 |
| XM_039087232.1 | XP_038943160.1 | obscurin isoform X14 |
| XM_039087223.1 | XP_038943151.1 | obscurin isoform X5 |
| XM_039087222.1 | XP_038943150.1 | obscurin isoform X4 |
| XM_039087236.1 | XP_038943164.1 | obscurin isoform X17 |
| XM_039087219.1 | XP_038943147.1 | obscurin isoform X1 |
| XM_039087254.1 | XP_038943182.1 | obscurin isoform X32 |
| XM_039087257.1 | XP_038943185.1 | obscurin isoform X34 |
| XM_039087256.1 | XP_038943184.1 | obscurin isoform X33 |
| XM_039087253.1 | XP_038943181.1 | obscurin isoform X32 |
| XM_039087252.1 | XP_038943180.1 | obscurin isoform X31 |
| XM_039087251.1 | XP_038943179.1 | obscurin isoform X31 |
| XM_039087258.1 | XP_038943186.1 | obscurin isoform X35 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
12631729 | RGD |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in M band |
IDA
IDA: Inferred from direct assay
|
12631729 | RGD |
| located in Z disc |
IDA
IDA: Inferred from direct assay
|
12631729 | RGD |
| located in sarcomere |
IDA
IDA: Inferred from direct assay
|
12631729 | RGD |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
obscurin |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS09736 | OBSCN Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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