NEK5 - NIMA related kinase 5 Gene

Homo sapiens

Gene ID: 341676 | Gene type: protein coding

About NEK5

Cytogenetic location: 13q14.3 Genomic coordinates (GRCh38): 13:52,033,611-52,129,073 (from NCBI)

This gene has 8 transcripts (splice variants), 186 orthologues and 8 paralogues. Biased expression in testis (RPKM 3.0), lung (RPKM 0.4) and 1 other tissue.

Summary

Predicted to enable ATP binding activity; metal ion binding activity; and protein kinase activity. Predicted to be involved in protein phosphorylation. Predicted to act upstream of or within positive regulation of cysteine-type endopeptidase activity and positive regulation of striated muscle cell differentiation. [provided by Alliance of Genome Resources, Apr 2022]

NEK5 Products(2)

mRNA	Protein	Name
NM_001365552.1	NP_001352481.1	serine/threonine-protein kinase Nek5 isoform 2
NM_199289.3	NP_954983.1	serine/threonine-protein kinase Nek5 isoform 1

NEK5 Protein Structure

Pkinase

0
200
400
600
708 a.a.

Protein Preferred Names

Protein Names

serine/threonine-protein kinase Nek5

NIMA (never in mitosis gene a)-related kinase 5

Related Diseases

Diseases

Alias

Bardet-Biedl Syndrome 1

BBS1	Bardet-Biedl Syndrome 1, Modifier Of
Bardet-Biedl Syndrome	BBS
Bardet-Biedl Syndrome, Type 1	Laurence-Moon-Bardet-Biedl Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09196	NEK5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	NEK5	VGNC	VGNC:68458
Macaca mulatta	NEK5	VGNC	VGNC:75310
Rattus norvegicus	NEK5	RGD	RGD:1593817
Bos taurus	NEK5	VGNC	VGNC:31996
Mus musculus	NEK5	MGD	MGI:2142824