NEK5 - NIMA related kinase 5 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 341676

About NEK5

Cytogenetic location: 13q14.3 Genomic coordinates (GRCh38): 13:52,033,611-52,129,073 (from NCBI)

This gene has 8 transcripts (splice variants), 186 orthologues and 8 paralogues. Biased expression in testis (RPKM 3.0), lung (RPKM 0.4) and 1 other tissue.

Summary

Predicted to enable ATP binding activity; metal ion binding activity; and protein kinase activity. Predicted to be involved in protein phosphorylation. Predicted to act upstream of or within positive regulation of cysteine-type endopeptidase activity and positive regulation of striated muscle cell differentiation. [provided by Alliance of Genome Resources, Apr 2022]

NEK5 Products (2)

mRNA Protein Name
NM_001365552.1 NP_001352481.1 serine/threonine-protein kinase Nek5 isoform 2
NM_199289.3 NP_954983.1 serine/threonine-protein kinase Nek5 isoform 1

NEK5 Protein Structure

Pkinase

Pkinase: Protein kinase domain (4 - 259)

  • 0
  • 200
  • 400
  • 600
  • 708 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase Nek5

  • NIMA (never in mitosis gene a)-related kinase 5

Related Diseases

Diseases Alias
Bardet-Biedl Syndrome 1

  • BBS1

  • Bardet-Biedl Syndrome 1, Modifier Of

  • Bardet-Biedl Syndrome

  • BBS

  • Bardet-Biedl Syndrome, Type 1

  • Laurence-Moon-Bardet-Biedl Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09196 NEK5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus NEK5 VGNC VGNC:68458
Macaca mulatta NEK5 VGNC VGNC:75310
Rattus norvegicus NEK5 RGD RGD:1593817
Bos taurus NEK5 VGNC VGNC:31996
Mus musculus NEK5 MGD MGI:2142824
Others NEK5 NCBI