TMC3 - transmembrane channel like 3 Gene
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 342125
About TMC3
Cytogenetic location: 15q25.1
Genomic coordinates (GRCh38): 15:81,331,088-81,374,213 (from NCBI)
This gene has 3 transcripts (splice variants), 195 orthologues and 7 paralogues. Low expression observed in reference dataset.
Summary
Predicted to enable mechanosensitive ion channel activity. Predicted to be involved in ion transmembrane transport. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
TMC3 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001080532.3 | NP_001074001.1 | transmembrane channel-like protein 3 |
TMC3 Protein Structure
TMC
TMC: TMC domain (499 - 614)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1100 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
transmembrane channel-like protein 3 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Epidermodysplasia Verruciformis 1 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS14623 | TMC3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | TMC3 | RGD | RGD:1308063 |
| Macaca mulatta | TMC3 | VGNC | VGNC:79360 |
| Canis familiaris | TMC3 | VGNC | VGNC:47422 |
| Felis catus | TMC3 | VGNC | VGNC:80819 |
| Mus musculus | TMC3 | MGD | MGI:2669033 |
| Bos taurus | TMC3 | VGNC | VGNC:35919 |
| Others | TMC3 | NCBI |
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