NME9 - NME/NM23 family member 9 Gene

Also Known as NXL2; TXL2; TXL-2; TXNDC6; NM23-H9

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 347736

About NME9

Cytogenetic location: 3q22.3 Genomic coordinates (GRCh38): 3:138,261,436-138,329,851 (from NCBI)

This gene has 9 transcripts (splice variants), 193 orthologues and 8 paralogues. Ubiquitous expression in thyroid (RPKM 1.1), brain (RPKM 1.0) and 25 other tissues.

Summary

Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in nucleotide metabolic process. Predicted to be located in dynein axonemal particle. [provided by Alliance of Genome Resources, Apr 2022]

NME9 Products (8)

mRNA	Protein	Name
NM_001349018.2	NP_001335947.1	thioredoxin domain-containing protein 6 isoform a
NM_001349020.2	NP_001335949.1	thioredoxin domain-containing protein 6 isoform c
NM_001349021.2	NP_001335950.1	thioredoxin domain-containing protein 6 isoform d
NM_001349022.2	NP_001335951.1	thioredoxin domain-containing protein 6 isoform e
NM_001349023.2	NP_001335952.1	thioredoxin domain-containing protein 6 isoform f
NM_001349024.2	NP_001335953.1	thioredoxin domain-containing protein 6 isoform g
NM_001349025.2	NP_001335954.1	thioredoxin domain-containing protein 6 isoform g
NM_178130.4	NP_835231.1	thioredoxin domain-containing protein 6 isoform b

NME9 Protein Structure

Thioredoxin

NDK

0
100
200
300
330 a.a.

Protein Preferred Names	Protein Names
thioredoxin domain-containing protein 6	NME gene family member 9

Related Diseases

Diseases	Alias
Ciliary Dyskinesia, Primary, 6	Primary Ciliary Dyskinesia 6 CILD6 Ics6 Immotile Cilia Syndrome 6 Dyskinesia, Ciliary, Primary, 6
Primary Ciliary Dyskinesia	Immotile Cilia Syndrome Kartagener Syndrome Dextrocardia Bronchiectasis And Sinusitis Pcd Ciliary Motility Disorders Ciliary Motility Disorder Immotile Ciliary Syndrome Ciliary Dyskinesia Primary Ics Polynesian Bronchiectasis Dextrocardia-Bronchiectasis-Sinusitis Syndrome Immotile Cilia Syndrome, Kartagener Type Primary Ciliary Dyskinesia And Situs Inversus Primary Ciliary Dyskinesia, Kartagener Type Siewert Syndrome Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-184563S	(2S,10S,19S)-Amine-(CO-CH2-N-Me)9-CO-CH2-CH(NH-CO-CH2-CH2-2-piperidone-tetrahydropyran-pyrimidine-SO2-cyclopentane)-(CO-NH-CH2)2-CO-NH-CH(CH2-benzene)-(CO-NH-CH2)2-O-CH(cyclopropane)-COOH-7-MAD-MDCPT-d2		/	Unkown
HY-RS09380	NME9 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	NME9	VGNC	VGNC:75228
Felis catus	NME9	VGNC	VGNC:63839
Mus musculus	NME9	MGD	MGI:4359686
Canis familiaris	NME9	VGNC	VGNC:43860
Bos taurus	NME9	VGNC	VGNC:32131
Rattus norvegicus	NME9	RGD	RGD:1564871