Hsd3b1 - hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Gene

Rattus norvegicus

Gene ID: 360348 | Gene type: protein coding

About Hsd3b1

Hsd3b1 Products(1)

mRNA	Protein	Name
NM_001007719.3	NP_001007720.3	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables 3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity	IDA IDA: Inferred from direct assay	1537836	RGD
enables NAD binding	IDA IDA: Inferred from direct assay	1955079	RGD
enables steroid binding	IPI IPI: Inferred from physical interaction	1955079	RGD
enables steroid delta-isomerase activity	IDA IDA: Inferred from direct assay	1537836	RGD
enables testosterone dehydrogenase [NAD(P)+] activity	IDA IDA: Inferred from direct assay	1309351	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in C21-steroid hormone metabolic process	IDA IDA: Inferred from direct assay	19190754	RGD
involved in Leydig cell differentiation	IEP IEP: Inferred from expression pattern	18502897	RGD
involved in adrenal gland development	IEP IEP: Inferred from expression pattern	1935797	RGD
involved in biphenyl metabolic process	IEP IEP: Inferred from expression pattern	19071209	RGD
involved in cellular response to antibiotic	IEP IEP: Inferred from expression pattern	18655822	RGD
involved in cellular response to cAMP	IEP IEP: Inferred from expression pattern	1312436	RGD
involved in cellular response to dexamethasone stimulus	IEP IEP: Inferred from expression pattern	20075416	RGD
involved in cellular response to fibroblast growth factor stimulus	IEP IEP: Inferred from expression pattern	17494997	RGD
involved in cellular response to follicle-stimulating hormone stimulus	IEP IEP: Inferred from expression pattern	20810564	RGD
involved in cellular response to glucose stimulus	IEP IEP: Inferred from expression pattern	18353182	RGD
involved in cellular response to gonadotropin stimulus	IEP IEP: Inferred from expression pattern	8142315	RGD
involved in cellular response to hydrogen peroxide	IEP IEP: Inferred from expression pattern	16374549	RGD
involved in cellular response to insulin stimulus	IEP IEP: Inferred from expression pattern	2177628	RGD
involved in cellular response to luteinizing hormone stimulus	IEP IEP: Inferred from expression pattern	1312436	RGD
involved in cellular response to mercury ion	IEP IEP: Inferred from expression pattern	2253967	RGD
involved in cellular response to methylmercury	IEP IEP: Inferred from expression pattern	2253967	RGD
involved in cellular response to transforming growth factor beta stimulus	IEP IEP: Inferred from expression pattern	18511507	RGD
involved in dibenzo-p-dioxin metabolic process	IEP IEP: Inferred from expression pattern	18637154	RGD
involved in diterpenoid metabolic process	IEP IEP: Inferred from expression pattern	1312436	RGD
involved in female gonad development	IEP IEP: Inferred from expression pattern	8439611	RGD
involved in granulocyte differentiation	IEP IEP: Inferred from expression pattern	18401763	RGD
involved in hippocampus development	IEP IEP: Inferred from expression pattern	21047951	RGD
involved in insecticide metabolic process	IEP IEP: Inferred from expression pattern	18401575	RGD
involved in male gonad development	IEP IEP: Inferred from expression pattern	18772241	RGD
involved in maternal process involved in female pregnancy	IEP IEP: Inferred from expression pattern	17257522	RGD
involved in organic acid metabolic process	IEP IEP: Inferred from expression pattern	17400581	RGD
involved in phenol-containing compound metabolic process	IEP IEP: Inferred from expression pattern	19429456	RGD
involved in phosphatidylcholine metabolic process	IEP IEP: Inferred from expression pattern	2590715	RGD
involved in progesterone biosynthetic process	IDA IDA: Inferred from direct assay	1955079	RGD
involved in response to L-ascorbic acid	IEP IEP: Inferred from expression pattern	17280759	RGD
involved in response to activity	IEP IEP: Inferred from expression pattern	18923565	RGD
involved in response to alkaloid	IEP IEP: Inferred from expression pattern	18772241	RGD
involved in response to arsenic-containing substance	IEP IEP: Inferred from expression pattern	16483355	RGD
involved in response to cadmium ion	IEP IEP: Inferred from expression pattern	18972398	RGD
involved in response to calcium ion	IEP IEP: Inferred from expression pattern	16472573	RGD
involved in response to corticosterone	IEP IEP: Inferred from expression pattern	18335507	RGD
involved in response to estradiol	IEP IEP: Inferred from expression pattern	16020475	RGD
involved in response to ethanol	IEP IEP: Inferred from expression pattern	17193892	RGD
involved in response to fatty acid	IEP IEP: Inferred from expression pattern	19130109	RGD
involved in response to fungicide	IEP IEP: Inferred from expression pattern	17485193	RGD
involved in response to herbicide	IEP IEP: Inferred from expression pattern	20045047	RGD
involved in response to lead ion	IEP IEP: Inferred from expression pattern	18972398	RGD
involved in response to metal ion	IEP IEP: Inferred from expression pattern	17822870	RGD
involved in response to nutrient levels	IEP IEP: Inferred from expression pattern	19130109	RGD
involved in response to organic cyclic compound	IEP IEP: Inferred from expression pattern	18606229	RGD
involved in response to vitamin E	IEP IEP: Inferred from expression pattern	17280759	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	18772241	RGD
involved in steroid metabolic process	IDA IDA: Inferred from direct assay	1955079	RGD
involved in testosterone biosynthetic process	IEP IEP: Inferred from expression pattern	16467141	RGD
involved in toluene metabolic process	IEP IEP: Inferred from expression pattern	19110042	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrial crista	IDA IDA: Inferred from direct assay	9065457	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

3 beta-hydroxysteroid dehydrogenase 1	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I
3-beta-HSD I	3-beta-hydroxy-5-ene steroid dehydrogenase
3-beta-hydroxy-Delta(5)-steroid dehydrogenase	3-beta-hydroxysteroid 3-dehydrogenase
3betaH

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06401	HSD3B1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hsd3b1	NCBI	NCBI:3283

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