Ap1s1 - adaptor related protein complex 1 subunit sigma 1 Gene

Rattus norvegicus

Gene ID: 360785 | Gene type: protein coding

About Ap1s1

Summary

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in several processes, including cellular response to misfolded protein; protein monoubiquitination; and proteolysis involved in cellular protein catabolic process. Predicted to act upstream of or within retrograde transport, endosome to Golgi. Predicted to be located in Golgi apparatus; nucleus; and terminal bouton. Predicted to be part of AP-1 adaptor complex. Predicted to be active in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in MEDNIK syndrome. Orthologous to human AP1S1 (adaptor related protein complex 1 subunit sigma 1). [provided by Alliance of Genome Resources, Apr 2022]

Ap1s1 Products(1)

mRNA	Protein	Name
NM_001108331.2	NP_001101801.2	adaptor-related protein complex 1, sigma 1 subunit

Protein Preferred Names

Protein Names

adaptor-related protein complex 1, sigma 1 subunit

ubiquitin-conjugating enzyme E2 W

adaptor protein complex AP-1, sigma 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00781	AP1S1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ap1s1	NCBI	NCBI:1174

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