Sptlc1 - serine palmitoyltransferase, long chain base subunit 1 Gene

Rattus norvegicus

Also known as Lcb1; Spt1; LCB 1; SPT 1; RGD1306617

Gene ID: 361213 | Gene type: protein coding

About Sptlc1

Summary

Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in ceramide biosynthetic process; regulation of fat cell apoptotic process; and sphingosine biosynthetic process. Predicted to act upstream of or within positive regulation of lipophagy; sphinganine biosynthetic process; and sphingomyelin biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of SPOTS complex. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1A. Orthologous to human SPTLC1 (serine palmitoyltransferase long chain base subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Sptlc1 Products(1)

mRNA	Protein	Name
NM_001108406.1	NP_001101876.1	serine palmitoyltransferase 1

Protein Preferred Names

Protein Names

serine palmitoyltransferase 1

long chain base biosynthesis protein 1	serine palmitoyltransferase subunit 1
serine-palmitoyl-CoA transferase 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS21943	Sptlc1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13736	SPTLC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sptlc1	NCBI	NCBI:10558

Name
Email *

	Sorry, but the email address you supplied was invalid.