Lims2 - LIM zinc finger domain containing 2 Gene

Predicted to enable metal ion binding activity. Predicted to be involved in several processes, including cell-cell junction organization; positive regulation of integrin-mediated signaling pathway; and positive regulation of substrate adhesion-dependent cell spreading. Predicted to act upstream of or within negative regulation of apoptotic process; negative regulation of hepatocyte proliferation; and negative regulation of neural precursor cell proliferation. Predicted to be located in plasma membrane. Predicted to be active in cell-cell junction; cytoplasm; and focal adhesion. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2W. Orthologous to human LIMS2 (LIM zinc finger domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]