SPINK5 - Spink5 serine peptidase inhibitor, Kazal type 5 Gene

Rattus norvegicus

Gene ID: 361319 | Gene type: protein coding

About SPINK5

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in epidermal cell differentiation; negative regulation of Antibacterial peptide production; and negative regulation of serine-type endopeptidase activity. Predicted to act upstream of or within negative regulation of serine-type peptidase activity and regulation of cell adhesion. Predicted to be located in several cellular components, including endoplasmic reticulum membrane; epidermal lamellar body; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in Netherton syndrome. Orthologous to human SPINK5 (serine peptidase inhibitor Kazal type 5). [provided by Alliance of Genome Resources, Apr 2022]

SPINK5 Products(1)

mRNA	Protein	Name
NM_001170606.1	NP_001164077.1	serine protease inhibitor Kazal-type 5 precursor

Protein Preferred Names

Protein Names

serine protease inhibitor Kazal-type 5

serine protease inhibitor Kazal-type 5-like

serine protease inhibitor, Kazal type 5

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13682	SPINK5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	SPINK5	NCBI	NCBI:11005

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