Gab1 - GRB2-associated binding protein 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361388

Summary

Involved in response to hepatocyte growth factor. Predicted to be located in cell-cell junction and cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 26. Orthologous to human GAB1 (GRB2 associated binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Gab1 Products (1)

mRNA Protein Name
NM_001108444.1 NP_001101914.1 GRB2-associated-binding protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16187300 RGD
Biological Process GO Annotation Evidence References Source
involved in response to hepatocyte growth factor IPI
IPI: Inferred from physical interaction
16187300 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GRB2-associated-binding protein 1

  • growth factor receptor bound protein 2-associated protein 1

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13404 Capmatinib 99.71% Yes
HY-13404C Capmatinib dihydrochloride hydrate 99.67% Yes
HY-13404A Capmatinib dihydrochloride 99.82% Yes
HY-13404B Capmatinib hydrochloride 99.48% Unkown

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05197 GAB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10503 PIGU Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gab1 NCBI NCBI:2549