Tent2 - terminal nucleotidyltransferase 2 Gene

Also Known as Papd4

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 361878

Summary

Predicted to enable 5'-3' RNA polymerase activity and polynucleotide adenylyltransferase activity. Involved in dark adaptation; nervous system development; and retina development in camera-type eye. Located in cytosol and nucleus. Orthologous to human TENT2 (terminal nucleotidyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Tent2 Products (1)

mRNA	Protein	Name
NM_001008372.2	NP_001008373.1	poly(A) RNA polymerase GLD2

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	References	Source
involved in RNA polyadenylation at postsynapse	IDA IDA: Inferred from direct assay	22727665	RGD
involved in RNA polyadenylation at postsynapse	IEP IEP: Inferred from expression pattern	22727665	RGD
involved in dark adaptation	IEP IEP: Inferred from expression pattern	23700402	RGD
involved in hippocampus development	IEP IEP: Inferred from expression pattern	24074826	RGD
involved in neuron differentiation	IEP IEP: Inferred from expression pattern	23933240	RGD
involved in positive regulation of protein targeting to membrane	IMP IMP: Inferred from mutant phenotype	23678131	RGD
involved in postsynaptic modulation of chemical synaptic transmission	IDA IDA: Inferred from direct assay	22727665	RGD
involved in postsynaptic modulation of chemical synaptic transmission	IMP IMP: Inferred from mutant phenotype	22727665	RGD
involved in regulation of translation at postsynapse	IDA IDA: Inferred from direct assay	22727665	RGD
involved in regulation of translation at postsynapse	IEP IEP: Inferred from expression pattern	22727665	RGD
involved in regulation of translation at postsynapse	IMP IMP: Inferred from mutant phenotype	22727665	RGD
involved in retina development in camera-type eye	IEP IEP: Inferred from expression pattern	23700402	RGD

Cellular Component GO Annotation	Evidence	References	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	22727665	RGD
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	22727665	RGD
is active in perforant pathway to dendrate granule cell synapse	IDA IDA: Inferred from direct assay	22727665	RGD
is active in perforant pathway to dendrate granule cell synapse	IMP IMP: Inferred from mutant phenotype	22727665	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	22727665	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
poly(A) RNA polymerase GLD2	PAP associated domain containing 4 PAP-associated domain-containing protein 4 poly(A) RNA polymerase D4, non-canonical

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14366	TENT2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tent2	NCBI	NCBI:167153