Sohlh1 - spermatogenesis and oogenesis specific basic helix-loop-helix 1 Gene

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Predicted to be involved in oocyte differentiation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within gamete generation; ovarian follicle development; and positive regulation of transcription, DNA-templated. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in ovarian dysgenesis 5 and spermatogenic failure 32. Orthologous to human SOHLH1 (spermatogenesis and oogenesis specific basic helix-loop-helix 1). [provided by Alliance of Genome Resources, Apr 2022]