2. Gene
  3. Polr3b - RNA polymerase III subunit B Gene

Polr3b - RNA polymerase III subunit B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1565311

Gene ID: 362858 | Gene type: protein coding

About Polr3b

Summary

Predicted to enable DNA binding activity; metal ion binding activity; and ribonucleoside binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in positive regulation of innate immune response and positive regulation of interferon-beta production. Predicted to be part of RNA polymerase III complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 8 with or without oligodontia and-or hypogonadotropic hypogonadism. Orthologous to human POLR3B (RNA polymerase III subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Polr3b Products(1)

mRNA Protein Name
NM_001191878.1 NP_001178807.1 DNA-directed RNA polymerase III subunit RPC2
Protein Preferred Names Protein Names

DNA-directed RNA polymerase III subunit RPC2

polymerase (RNA) III (DNA directed) polypeptide B

polymerase (RNA) III subunit B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10856 POLR3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr3b NCBI NCBI:55703