Ppfia2 - PTPRF interacting protein alpha 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362876

Summary

A structural constituent of presynapse. Involved in regulation of synaptic vesicle exocytosis. Is active in glutamatergic synapse. Orthologous to human PPFIA2 (PTPRF interacting protein alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Ppfia2 Products (1)

mRNA Protein Name
NM_001108745.1 NP_001102215.1 liprin-alpha-2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables structural constituent of postsynaptic density EXP
EXP: Inferred from Experiment
30021165 RGD
enables structural constituent of postsynaptic density IDA
IDA: Inferred from direct assay
30021165 RGD
enables structural constituent of postsynaptic density IMP
IMP: Inferred from mutant phenotype
30021165 RGD
enables structural constituent of presynapse IDA
IDA: Inferred from direct assay
23751498 RGD
enables structural constituent of presynapse IMP
IMP: Inferred from mutant phenotype
23751498 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of synaptic vesicle exocytosis IDA
IDA: Inferred from direct assay
23751498 RGD
involved in regulation of synaptic vesicle exocytosis IMP
IMP: Inferred from mutant phenotype
23751498 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
30021165 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23751498 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
23751498 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
30021165 RGD
is active in postsynaptic density IMP
IMP: Inferred from mutant phenotype
30021165 RGD
is active in postsynaptic specialization IDA
IDA: Inferred from direct assay
11931740 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
11931740 RGD
is active in synaptic vesicle IDA
IDA: Inferred from direct assay
11931740 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

liprin-alpha-2

  • protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10940 PPFIA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppfia2 NCBI NCBI:8499