Cadm1 - cell adhesion molecule 1 Gene

Also Known as Igsf4; TSLC1; Igsf4a; Necl-2; SynCAM; TSLC-1; sgigsf

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363058

Summary

Enables cell adhesion molecule binding activity. Involved in brain development and liver development. Located in neuron projection; plasma membrane; and postsynaptic density. Biomarker of hepatocellular carcinoma and lung adenocarcinoma. Human ortholog(s) of this gene implicated in breast carcinoma and prostate Cancer. Orthologous to human CADM1 (cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Cadm1 Products (1)

mRNA Protein Name
NM_001012201.2 NP_001012201.1 cell adhesion molecule 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cell adhesion molecule binding IPI
IPI: Inferred from physical interaction
18003830 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
27756895 RGD
Biological Process GO Annotation Evidence References Source
involved in liver development IMP
IMP: Inferred from mutant phenotype
17326163 RGD
involved in negative regulation of ERBB4 signaling pathway IMP
IMP: Inferred from mutant phenotype
23769722 RGD
involved in negative regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
23769722 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
23769722 RGD
located in postsynaptic density IDA
IDA: Inferred from direct assay
27756895 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cell adhesion molecule 1

  • immunoglobulin superfamily, member 4

  • immunoglobulin superfamily, member 4A

  • nectin-like protein 2

  • spermatogenic immunoglobulin superfamily

  • synaptic cell adhesion molecule

  • tumor suppressor in lung cancer 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS17973 Cadm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01819 CADM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24444 Cadm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cadm1 NCBI NCBI:23705