Dixdc1 - DIX domain containing 1 Gene

Rattus norvegicus

Also known as Ccd1

Gene ID: 363062 | Gene type: protein coding

About Dixdc1

Summary

Enables mitogen-activated protein kinase kinase kinase binding activity. Involved in cerebellar cortex development; positive regulation of JNK cascade; and positive regulation of axonogenesis. Located in axon terminus; cytoplasm; and neuronal cell body. Part of protein-containing complex. Orthologous to human DIXDC1 (DIX domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Dixdc1 Products(1)

mRNA	Protein	Name
NM_001395147.1	NP_001382076.1	dixin

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables mitogen-activated protein kinase kinase kinase binding	IDA IDA: Inferred from direct assay	19339625	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cerebellar cortex development	IMP IMP: Inferred from mutant phenotype	19339625	RGD
involved in positive regulation of JNK cascade	IMP IMP: Inferred from mutant phenotype	19339625	RGD
involved in positive regulation of axonogenesis	IMP IMP: Inferred from mutant phenotype	19339625	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in axon terminus	IDA IDA: Inferred from direct assay	19339625	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	19339625	RGD
part of protein-containing complex	IDA IDA: Inferred from direct assay	19339625	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dixin

DIX domain-containing protein 1	coiled-coil protein DIX1
coiled-coil-DIX1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03785	DIXDC1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dixdc1	NCBI	NCBI:85458

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