Nphp3 - nephrocystin 3 Gene

Predicted to be involved in several processes, including animal organ development; determination of left/right symmetry; and photoreceptor cell maintenance. Predicted to act upstream of or within several processes, including extracellular matrix organization; non-motile cilium assembly; and positive regulation of protein binding activity. Predicted to be located in ciliary base and ciliary inversin compartment. Human ortholog(s) of this gene implicated in Meckel syndrome 7; nephronophthisis; nephronophthisis 3; and renal-hepatic-pancreatic dysplasia. Orthologous to human NPHP3 (nephrocystin 3). [provided by Alliance of Genome Resources, Apr 2022]