Sgo1 - shugoshin 1 Gene

Predicted to enable kinase binding activity. Predicted to be involved in attachment of spindle microtubules to kinetochore and nuclear division. Predicted to act upstream of or within centriole-centriole cohesion and meiotic chromosome segregation. Predicted to be located in several cellular components, including condensed chromosome, centromeric region; microtubule cytoskeleton; and nucleoplasm. Predicted to be active in kinetochore. Human ortholog(s) of this gene implicated in chronic atrial and intestinal dysrhythmia. Orthologous to human SGO1 (shugoshin 1). [provided by Alliance of Genome Resources, Apr 2022]