Traf3ip1 - TRAF3 interacting protein 1 Gene

Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including cilium organization; negative regulation of macromolecule metabolic process; and regulation of microtubule Cytoskeleton organization. Predicted to act upstream of or within several processes, including embryonic organ development; negative regulation of interferon-beta production; and negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. Predicted to be located in ciliary base; ciliary tip; and ciliary transition zone. Predicted to be part of intraciliary transport particle B. Predicted to be active in axoneme; centrosome; and ciliary basal body. Human ortholog(s) of this gene implicated in Senior-Loken syndrome. Orthologous to human TRAF3IP1 (TRAF3 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]