Piga - phosphatidylinositol glycan anchor biosynthesis, class A Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363464

Summary

Predicted to enable phosphatidylinositol N-acetylglucosaminyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to act upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 2 and paroxysmal nocturnal hemoglobinuria. Orthologous to human PIGA (phosphatidylinositol glycan anchor biosynthesis class A). [provided by Alliance of Genome Resources, Apr 2022]

Piga Products (2)

mRNA Protein Name
NM_001108816.2 NP_001102286.1 phosphatidylinositol N-acetylglucosaminyltransferase subunit A isoform 2
NM_001401036.1 NP_001387965.1 phosphatidylinositol N-acetylglucosaminyltransferase subunit A isoform 1
Protein Preferred Names Protein Names

phosphatidylinositol N-acetylglucosaminyltransferase subunit A

  • N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein

  • phosphatidylinositol glycan, class A

Orthologs Information

Species Symbol Source ID
Homo sapiens Piga NCBI NCBI:5277