Piga - phosphatidylinositol glycan anchor biosynthesis, class A Gene

Rattus norvegicus

Gene ID: 363464 | Gene type: protein coding

About Piga

Summary

Predicted to enable phosphatidylinositol N-acetylglucosaminyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to act upstream of or within cellular response to Leukemia Inhibitory Factor. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 2 and paroxysmal nocturnal hemoglobinuria. Orthologous to human PIGA (phosphatidylinositol glycan anchor biosynthesis class A). [provided by Alliance of Genome Resources, Apr 2022]

Piga Products(2)

mRNA	Protein	Name
NM_001108816.2	NP_001102286.1	phosphatidylinositol N-acetylglucosaminyltransferase subunit A isoform 2
NM_001401036.1	NP_001387965.1	phosphatidylinositol N-acetylglucosaminyltransferase subunit A isoform 1

Protein Preferred Names

Protein Names

phosphatidylinositol N-acetylglucosaminyltransferase subunit A

N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein

phosphatidylinositol glycan, class A

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10487	PIGA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Piga	NCBI	NCBI:5277

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