Tafazzin - tafazzin, phospholipid-lysophospholipid transacylase Gene

Rattus norvegicus

Also known as Taz

Gene ID: 363521 | Gene type: protein coding

About Tafazzin

Summary

Predicted to enable 1-acylglycerophosphocholine O-acyltransferase activity. Involved in positive regulation of ATP biosynthetic process and positive regulation of cardiolipin metabolic process. Predicted to be located in mitochondrial inner membrane and mitochondrial outer membrane. Predicted to be active in mitochondrial membrane. Human ortholog(s) of this gene implicated in Barth syndrome and dilated cardiomyopathy. Orthologous to human TAFAZZIN (tafazzin, phospholipid-lysophospholipid transacylase). [provided by Alliance of Genome Resources, Apr 2022]

Tafazzin Products(1)

mRNA	Protein	Name
NM_001025748.1	NP_001020919.1	tafazzin

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of ATP biosynthetic process	IMP IMP: Inferred from mutant phenotype	20348225	RGD
involved in positive regulation of cardiolipin metabolic process	IMP IMP: Inferred from mutant phenotype	20348225	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

tafazzin

Barth syndrome)	cardiomyopathy, dilated 3A (X-linked)
endocardial fibroelastosis 2	tafazzin (cardiomyopathy, dilated 3A (X-linked)
tafazzin (cardiomyopathy, dilated 3A (X-linked)	endocardial fibroelastosis 2
Barth syndrome)

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14184	TAFAZZIN Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tafazzin	NCBI	NCBI:6901

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