Tafazzin - tafazzin, phospholipid-lysophospholipid transacylase Gene

Also Known as Taz

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363521

Summary

Predicted to enable 1-acylglycerophosphocholine O-acyltransferase activity. Involved in positive regulation of ATP biosynthetic process and positive regulation of cardiolipin metabolic process. Predicted to be located in mitochondrial inner membrane and mitochondrial outer membrane. Predicted to be active in mitochondrial membrane. Human ortholog(s) of this gene implicated in Barth syndrome and dilated cardiomyopathy. Orthologous to human TAFAZZIN (tafazzin, phospholipid-lysophospholipid transacylase). [provided by Alliance of Genome Resources, Apr 2022]

Tafazzin Products (1)

mRNA Protein Name
NM_001025748.1 NP_001020919.1 tafazzin

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of ATP biosynthetic process IMP
IMP: Inferred from mutant phenotype
20348225 RGD
involved in positive regulation of cardiolipin metabolic process IMP
IMP: Inferred from mutant phenotype
20348225 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tafazzin

  • Barth syndrome)

  • cardiomyopathy, dilated 3A (X-linked)

  • endocardial fibroelastosis 2

  • tafazzin (cardiomyopathy, dilated 3A (X-linked)

  • tafazzin (cardiomyopathy, dilated 3A (X-linked)

  • endocardial fibroelastosis 2

  • Barth syndrome)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14184 TAFAZZIN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tafazzin NCBI NCBI:6901