Abi3bp - ABI family member 3 binding protein Gene
Also Known as RGD1562717
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 363767
Summary
Enables actin filament binding activity. Involved in regulation of actin Cytoskeleton reorganization; regulation of dendritic spine morphogenesis; and regulation of postsynaptic density assembly. Located in dendrite; lamellipodium; and postsynaptic density. Orthologous to human ABI3BP (ABI family member 3 binding protein). [provided by Alliance of Genome Resources, Apr 2022]
Abi3bp Products (50)
| mRNA | Protein | Name |
|---|---|---|
| XM_017598136.2 | XP_017453625.1 | target of Nesh-SH3 isoform X19 |
| XM_017598128.2 | XP_017453617.1 | target of Nesh-SH3 isoform X12 |
| XM_017598132.2 | XP_017453621.1 | target of Nesh-SH3 isoform X17 |
| XM_017598129.2 | XP_017453618.1 | target of Nesh-SH3 isoform X15 |
| XM_017598127.2 | XP_017453616.1 | target of Nesh-SH3 isoform X11 |
| XM_039088837.1 | XP_038944765.1 | target of Nesh-SH3 isoform X13 |
| XM_017598123.2 | XP_017453612.1 | target of Nesh-SH3 isoform X7 |
| XM_039088834.1 | XP_038944762.1 | target of Nesh-SH3 isoform X2 |
| XM_017598124.2 | XP_017453613.1 | target of Nesh-SH3 isoform X8 |
| XM_017598120.2 | XP_017453609.1 | target of Nesh-SH3 isoform X3 |
| XM_017598121.2 | XP_017453610.1 | target of Nesh-SH3 isoform X5 |
| XM_017598122.2 | XP_017453611.1 | target of Nesh-SH3 isoform X6 |
| XM_017598133.2 | XP_017453622.1 | target of Nesh-SH3 isoform X18 |
| XM_017598125.2 | XP_017453614.1 | target of Nesh-SH3 isoform X9 |
| XM_017598131.2 | XP_017453620.1 | target of Nesh-SH3 isoform X16 |
| XM_039088838.1 | XP_038944766.1 | target of Nesh-SH3 isoform X14 |
| XM_017598126.2 | XP_017453615.1 | target of Nesh-SH3 isoform X10 |
| XM_039088835.1 | XP_038944763.1 | target of Nesh-SH3 isoform X4 |
| XM_017598119.2 | XP_017453608.1 | target of Nesh-SH3 isoform X1 |
| XM_017598145.2 | XP_017453634.1 | target of Nesh-SH3 isoform X36 |
| XM_039088852.1 | XP_038944780.1 | target of Nesh-SH3 isoform X40 |
| XM_039088849.1 | XP_038944777.1 | target of Nesh-SH3 isoform X37 |
| XM_017598143.2 | XP_017453632.1 | target of Nesh-SH3 isoform X34 |
| XM_039088844.1 | XP_038944772.1 | target of Nesh-SH3 isoform X28 |
| XM_017598144.2 | XP_017453633.1 | target of Nesh-SH3 isoform X35 |
| XM_039088848.1 | XP_038944776.1 | target of Nesh-SH3 isoform X32 |
| XM_039088846.1 | XP_038944774.1 | target of Nesh-SH3 isoform X30 |
| XM_039088847.1 | XP_038944775.1 | target of Nesh-SH3 isoform X31 |
| XM_039088843.1 | XP_038944771.1 | target of Nesh-SH3 isoform X27 |
| XM_039088842.1 | XP_038944770.1 | target of Nesh-SH3 isoform X26 |
| XM_006248233.4 | XP_006248295.1 | target of Nesh-SH3 isoform X24 |
| XM_017598142.2 | XP_017453631.1 | target of Nesh-SH3 isoform X33 |
| XM_039088845.1 | XP_038944773.1 | target of Nesh-SH3 isoform X29 |
| XM_039088841.1 | XP_038944769.1 | target of Nesh-SH3 isoform X25 |
| XM_008768669.3 | XP_008766891.1 | target of Nesh-SH3 isoform X23 |
| XM_039088840.1 | XP_038944768.1 | target of Nesh-SH3 isoform X22 |
| XM_039088839.1 | XP_038944767.1 | target of Nesh-SH3 isoform X21 |
| XM_006248232.4 | XP_006248294.1 | target of Nesh-SH3 isoform X20 |
| XM_039088859.1 | XP_038944787.1 | target of Nesh-SH3 isoform X47 |
| XM_039088856.1 | XP_038944784.1 | target of Nesh-SH3 isoform X44 |
| XM_039088855.1 | XP_038944783.1 | target of Nesh-SH3 isoform X43 |
| XM_039088862.1 | XP_038944790.1 | target of Nesh-SH3 isoform X50 |
| XM_039088861.1 | XP_038944789.1 | target of Nesh-SH3 isoform X49 |
| XM_039088854.1 | XP_038944782.1 | target of Nesh-SH3 isoform X42 |
| XM_039088860.1 | XP_038944788.1 | target of Nesh-SH3 isoform X48 |
| XM_039088858.1 | XP_038944786.1 | target of Nesh-SH3 isoform X46 |
| XM_039088853.1 | XP_038944781.1 | target of Nesh-SH3 isoform X41 |
| XM_039088850.1 | XP_038944778.1 | target of Nesh-SH3 isoform X38 |
| XM_039088857.1 | XP_038944785.1 | target of Nesh-SH3 isoform X45 |
| XM_039088851.1 | XP_038944779.1 | target of Nesh-SH3 isoform X39 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables actin filament binding |
IDA
IDA: Inferred from direct assay
|
22485184 | RGD |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in actin cytoskeleton organization |
IMP
IMP: Inferred from mutant phenotype
|
22485184 | RGD |
| involved in regulation of dendritic spine morphogenesis |
IMP
IMP: Inferred from mutant phenotype
|
22485184 | RGD |
| involved in regulation of postsynaptic density assembly |
IMP
IMP: Inferred from mutant phenotype
|
22485184 | RGD |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in dendritic shaft |
IDA
IDA: Inferred from direct assay
|
22496823 | RGD |
| located in dendritic spine |
IDA
IDA: Inferred from direct assay
|
22485184 | RGD |
| located in lamellipodium |
IDA
IDA: Inferred from direct assay
|
18480067 | RGD |
| located in postsynaptic density |
IDA
IDA: Inferred from direct assay
|
22485184 | RGD |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
target of Nesh-SH3 |
|
Related Agents
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Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS00101 | ABI3BP Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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