Sptlc2 - serine palmitoyltransferase, long chain base subunit 2 Gene

Rattus norvegicus

Also known as LCB 2; Pomt2; SPT 2

Gene ID: 366697 | Gene type: protein coding

About Sptlc2

Summary

Predicted to enable serine C-palmitoyltransferase activity. Predicted to be involved in adipose tissue development; ceramide biosynthetic process; and sphingosine biosynthetic process. Predicted to act upstream of or within positive regulation of lipophagy; sphinganine biosynthetic process; and sphingomyelin biosynthetic process. Predicted to be integral component of membrane. Predicted to be part of serine C-palmitoyltransferase complex. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1C. Orthologous to human SPTLC2 (serine palmitoyltransferase long chain base subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Sptlc2 Products(1)

mRNA	Protein	Name
NM_001037097.2	NP_001032174.1	serine palmitoyltransferase 2

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in response to immobilization stress	IEP IEP: Inferred from expression pattern	34449011	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

serine palmitoyltransferase 2

long chain base biosynthesis protein 2	protein-O-mannosyltransferase 2
serine-palmitoyl-CoA transferase 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13737	SPTLC2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sptlc2	NCBI	NCBI:9517

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