Prkag2 - protein kinase AMP-activated non-catalytic subunit gamma 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 373545

Summary

Enables AMP binding activity and protein kinase binding activity. Contributes to AMP-activated protein kinase activity. Involved in regulation of catalytic activity. Part of nucleotide-activated protein kinase complex. Human ortholog(s) of this gene implicated in Wolff-Parkinson-White syndrome; glycogen storage disease; hypertrophic cardiomyopathy 6; and lethal congenital glycogen storage disease of heart. Orthologous to human PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2). [provided by Alliance of Genome Resources, Apr 2022]

Prkag2 Products (2)

mRNA Protein Name
NM_001398879.1 NP_001385808.1 5'-AMP-activated protein kinase subunit gamma-2 isoform 1
NM_184051.1 NP_908940.1 5'-AMP-activated protein kinase subunit gamma-2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables AMP binding IDA
IDA: Inferred from direct assay
16648175 RGD
contributes to AMP-activated protein kinase activity IDA
IDA: Inferred from direct assay
16648175 RGD
contributes to AMP-activated protein kinase activity IMP
IMP: Inferred from mutant phenotype
10698692 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
16648175 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of catalytic activity IDA
IDA: Inferred from direct assay
16648175 RGD
Cellular Component GO Annotation Evidence References Source
part of nucleotide-activated protein kinase complex IDA
IDA: Inferred from direct assay
10698692 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5'-AMP-activated protein kinase subunit gamma-2

  • AMP-activated protein kinase gamma2 subunit

  • AMPK gamma 2

  • adenosine monophosphate-activated protein kinase gamma 2-subunit

  • protein kinase, AMP-activated, gamma 2 non-catalytic subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11110 PRKAG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkag2 NCBI NCBI:51422