KCNJ14 - potassium inwardly rectifying channel subfamily J member 14 Gene

Also Known as IRK4; KIR2.4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3770

About KCNJ14

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:48,455,574-48,466,980 (from NCBI)

This gene has 2 transcripts (splice variants), 174 orthologues and 15 paralogues. Broad expression in testis (RPKM 1.5), skin (RPKM 1.2) and 21 other tissues.

Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type Potassium Channel, and probably has a role in controlling the excitability of motor neurons. [provided by RefSeq, Feb 2013]

KCNJ14 Products (1)

mRNA Protein Name
NM_013348.4 NP_037480.1 ATP-sensitive inward rectifier potassium channel 14

KCNJ14 Protein Structure

IRK

IRK: Inward rectifier potassium channel (53 - 379)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 436 a.a.
Protein Preferred Names Protein Names

ATP-sensitive inward rectifier potassium channel 14

  • inward rectifier K(+) channel Kir2.4

Related Diseases

Diseases Alias
Kluver-Bucy Syndrome

  • Bilateral Temporal Lobe Disorder

  • Klüver-Bucy Syndrome

  • Klver-Bucy Syndrome

  • Kluver Bucy Syndrome

  • Memory Loss, Extreme Sexual Behavior, Placidity, And Visual Distractibility

  • Post-Encephalitic Kluver Bucy Syndrome

  • Post-Traumatic Kluver Bucy Syndrome
Andersen Cardiodysrhythmic Periodic Paralysis

  • Andersen Syndrome

  • Andersen-Tawil Syndrome

  • LQT7

  • Long Qt Syndrome 7

  • Ats

  • Periodic Paralysis, Potassium-Sensitive Cardiodysrhythmic Type

  • Long Qt Syndrome Type 7

  • Andersen Tawil Syndrome

  • Potassium-Sensitive Cardiodysrhythmic Type

  • Lqts Type 7

  • Long Qt Syndrome-7
Severe Congenital Neutropenia 3

  • Kostmann Syndrome

  • Infantile Agranulocytosis

  • Kostmann Disease

  • Scn3

  • Severe Congenital Neutropenia Type 3
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07141 KCNJ14 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus KCNJ14 MGD MGI:2384820
Macaca mulatta KCNJ14 VGNC VGNC:73985
Rattus norvegicus KCNJ14 RGD RGD:628872
Bos taurus KCNJ14 VGNC VGNC:30457
Others KCNJ14 NCBI