Pram1 - PML-RAR alpha-regulated adaptor molecule 1 Gene

Mus musculus

Gene ID: 378460 | Gene type: protein coding

About Pram1

Summary

Predicted to enable protein kinase binding activity. Acts upstream of or within integrin-mediated signaling pathway and regulation of neutrophil degranulation. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in brain; oviduct; spinal cord; stomach; and testis. Orthologous to human PRAM1 (PML-RARA regulated adaptor molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Pram1 Products(1)

mRNA	Protein	Name
NM_001002842.2	NP_001002842.2	PML-RARA-regulated adapter molecule 1

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within integrin-mediated signaling pathway	IMP IMP: Inferred from mutant phenotype	15572693	MGI
acts upstream of or within regulation of neutrophil degranulation	IMP IMP: Inferred from mutant phenotype	15572693	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

PML-RARA-regulated adapter molecule 1

PRAM-1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11048	PRAM1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pram1	NCBI	NCBI:84106

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