2. Gene
  3. Lrch1 - leucine-rich repeats and calponin homology (CH) domain containing 1 Gene

Lrch1 - leucine-rich repeats and calponin homology (CH) domain containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Chdc1; mKIAA1016; 4832412D13Rik

Gene ID: 380916 | Gene type: protein coding

About Lrch1

Summary

Involved in cellular response to chemokine; negative regulation of GTPase activity; and negative regulation of T cell migration. Predicted to be active in cytoplasm. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; gut; and hemolymphoid system gland. Used to study multiple sclerosis. Orthologous to human LRCH1 (leucine rich repeats and calponin homology domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Lrch1 Products(2)

mRNA Protein Name
NM_001033439.3 NP_001028611.2 leucine-rich repeat and calponin homology domain-containing protein 1 isoform 1
NM_001252132.1 NP_001239061.1 leucine-rich repeat and calponin homology domain-containing protein 1 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
28028151 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to chemokine IMP
IMP: Inferred from mutant phenotype
28028151 MGI
involved in negative regulation of GTPase activity IDA
IDA: Inferred from direct assay
28028151 MGI
involved in negative regulation of T cell migration IMP
IMP: Inferred from mutant phenotype
28028151 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leucine-rich repeat and calponin homology domain-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07778 LRCH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrch1 NCBI NCBI:23143