Alg10b - asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase) Gene

Also Known as nse5; Deaf1; Gm917

Species: Mus musculus

Gene Type: protein coding
Gene ID: 380959

Summary

Predicted to enable dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity. Acts upstream of or within auditory receptor cell development and sensory perception of sound. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and respiratory system. Used to study nonsyndromic deafness. Human ortholog(s) of this gene implicated in long QT syndrome 2. Orthologous to several human genes including ALG10B (ALG10 alpha-1,2-glucosyltransferase B). [provided by Alliance of Genome Resources, Apr 2022]

Alg10b Products (1)

mRNA Protein Name
NM_001033441.3 NP_001028613.1 putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within auditory receptor cell development IMP
IMP: Inferred from mutant phenotype
24303013 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
24303013 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

  • alpha-1,2-glucosyltransferase ALG10-A

  • alpha-2-glucosyltransferase ALG10-B

  • asparagine-linked glycosylation 10 homolog B (yeast, alpha-1,2-glucosyltransferase)

  • asparagine-linked glycosylation protein 10 homolog B

  • potassium channel regulator 1

  • putative

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00587 ALG10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown