Gm960 - predicted gene 960 Gene

Also Known as Top6bl; TOPOVIBL

Species: Mus musculus

Gene Type: protein coding
Gene ID: 381196

Summary

Predicted to enable DNA Topoisomerase type II (double strand cut, ATP-hydrolyzing) activity. Involved in meiotic DNA double-strand break formation and reciprocal meiotic recombination. Predicted to be located in chromosome. Is expressed in ovary; primary oocyte; secondary oocyte; and testis. Human ortholog(s) of this gene implicated in gestational trophoblastic neoplasm. Orthologous to human C11orf80 (chromosome 11 open reading frame 80). [provided by Alliance of Genome Resources, Apr 2022]

Gm960 Products (1)

mRNA Protein Name
NM_001033447.3 NP_001028619.2 type 2 DNA topoisomerase 6 subunit B-like

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
26917764 MGI
Biological Process GO Annotation Evidence References Source
involved in meiotic DNA double-strand break formation IMP
IMP: Inferred from mutant phenotype
26917764 MGI
involved in reciprocal meiotic recombination IMP
IMP: Inferred from mutant phenotype
26917764 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

type 2 DNA topoisomerase 6 subunit B-like

  • type 2 DNA topoisomerase VI subunit B-like