Prdm12 - PR domain containing 12 Gene

Also Known as Gm998

Species: Mus musculus

Gene Type: protein coding
Gene ID: 381359

Summary

Predicted to enable Histone Methyltransferase binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within neurogenesis and positive regulation of histone H3-K9 methylation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including future brain and nervous system. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 8. Orthologous to human PRDM12 (PR/SET domain 12). [provided by Alliance of Genome Resources, Apr 2022]

Prdm12 Products (1)

mRNA Protein Name
NM_001123362.1 NP_001116834.1 PR domain zinc finger protein 12

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables histone chaperone activity IDA
IDA: Inferred from direct assay
26005867 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
26443638 MGI
acts upstream of or within neurogenesis IDA
IDA: Inferred from direct assay
19050759 MGI
acts upstream of or within protein methylation IDA
IDA: Inferred from direct assay
26005867 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PR domain zinc finger protein 12

  • PR domain-containing protein 12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11062 PRDM12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prdm12 NCBI NCBI:59335