Zcwpw1 - zinc finger, CW type with PWWP domain 1 Gene
Also Known as Gm1053
Species: Mus musculus
Summary
Enables methylated histone binding activity. Involved in meiosis I; positive regulation of DNA metabolic process; and spermatogenesis. Acts upstream of or within homologous chromosome pairing at meiosis. Located in XY body and nucleus. Is expressed in brain; lung; reproductive system; and thymus. Orthologous to human ZCWPW1 (zinc finger CW-type and PWWP domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Zcwpw1 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001005426.2 | NP_001005426.2 | zinc finger CW-type PWWP domain protein 1 |
| NM_001360023.1 | NP_001346952.1 | zinc finger CW-type PWWP domain protein 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables histone reader activity |
IDA
IDA: Inferred from direct assay
|
32374261 | MGI |
| enables methylated histone binding |
IDA
IDA: Inferred from direct assay
|
31453335 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within homologous chromosome pairing at meiosis |
IMP
IMP: Inferred from mutant phenotype
|
31453335 | MGI |
| involved in homologous chromosome pairing at meiosis |
IMP
IMP: Inferred from mutant phenotype
|
32352380 | MGI |
| involved in meiosis I |
IMP
IMP: Inferred from mutant phenotype
|
32374261 | MGI |
| involved in positive regulation of DNA recombination |
IMP
IMP: Inferred from mutant phenotype
|
31453335 | MGI |
| involved in positive regulation of double-strand break repair |
IMP
IMP: Inferred from mutant phenotype
|
31453335 | MGI |
| involved in spermatogenesis |
IMP
IMP: Inferred from mutant phenotype
|
31453335 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in XY body |
IDA
IDA: Inferred from direct assay
|
31453335 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
31453335 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
zinc finger CW-type PWWP domain protein 1 |
|