2. Gene
  3. ZCWPW1 - zinc finger CW-type and PWWP domain containing 1 Gene

ZCWPW1 - zinc finger CW-type and PWWP domain containing 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ZCW1

Gene ID: 55063 | Gene type: protein coding

About ZCWPW1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,400,872-100,428,703 (from NCBI)

This gene has 9 transcripts (splice variants), 111 orthologues and 1 paralogue. Broad expression in testis (RPKM 25.2), thyroid (RPKM 2.9) and 16 other tissues.

Summary

Enables methyl-CpG binding activity and methylated histone binding activity. Predicted to be involved in meiosis I; positive regulation of DNA metabolic process; and spermatogenesis. Predicted to act upstream of or within homologous chromosome pairing at meiosis. Predicted to be located in XY body. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZCWPW1 Products(18)

mRNA Protein Name
NM_001258008.3 NP_001244937.1 zinc finger CW-type PWWP domain protein 1 isoform 2
NM_001386008.1 NP_001372937.1 zinc finger CW-type PWWP domain protein 1 isoform 14
NM_001386009.1 NP_001372938.1 zinc finger CW-type PWWP domain protein 1 isoform 10
NM_001386010.1 NP_001372939.1 zinc finger CW-type PWWP domain protein 1 isoform 3
NM_001386011.1 NP_001372940.1 zinc finger CW-type PWWP domain protein 1 isoform 12
NM_001386012.1 NP_001372941.1 zinc finger CW-type PWWP domain protein 1 isoform 7
NM_001386013.1 NP_001372942.1 zinc finger CW-type PWWP domain protein 1 isoform 6
NM_001386015.1 NP_001372944.1 zinc finger CW-type PWWP domain protein 1 isoform 11
NM_001386016.1 NP_001372945.1 zinc finger CW-type PWWP domain protein 1 isoform 4
NM_001386017.1 NP_001372946.1 zinc finger CW-type PWWP domain protein 1 isoform 5
NM_001386018.1 NP_001372947.1 zinc finger CW-type PWWP domain protein 1 isoform 6
NM_001386019.1 NP_001372948.1 zinc finger CW-type PWWP domain protein 1 isoform 10
NM_001386020.1 NP_001372949.1 zinc finger CW-type PWWP domain protein 1 isoform 2
NM_001386021.1 NP_001372950.1 zinc finger CW-type PWWP domain protein 1 isoform 13
NM_001386022.1 NP_001372951.1 zinc finger CW-type PWWP domain protein 1 isoform 8
NM_001386023.1 NP_001372952.1 zinc finger CW-type PWWP domain protein 1 isoform 9
NM_001388066.1 NP_001374995.1 zinc finger CW-type PWWP domain protein 1 isoform 15
NM_017984.6 NP_060454.3 zinc finger CW-type PWWP domain protein 1 isoform 1

ZCWPW1 Protein Structure

zf-CW

zf-CW: CW-type Zinc Finger (256 - 302)

PWWP

PWWP: PWWP domain (317 - 409)

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  • 648 a.a.
Protein Preferred Names Protein Names

zinc finger CW-type PWWP domain protein 1

zinc finger CW-type and PWWP domain 1

Related Diseases

Diseases Alias
Ciliary Dyskinesia, Primary, 6

Primary Ciliary Dyskinesia 6

CILD6

Ics6

Immotile Cilia Syndrome 6

Dyskinesia, Ciliary, Primary, 6
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16009 ZCWPW1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZCWPW1 MGD MGI:2685899
Felis catus ZCWPW1 VGNC VGNC:67199
Rattus norvegicus ZCWPW1 RGD RGD:1305405
Canis familiaris ZCWPW1 VGNC VGNC:48575
Bos taurus ZCWPW1 VGNC VGNC:37125
Macaca mulatta ZCWPW1 VGNC VGNC:79393