Drc1 - dynein regulatory complex subunit 1 Gene

Also Known as Gm1060; Ccdc164; b2b1654Clo

Species: Mus musculus

Gene Type: protein coding
Gene ID: 381738

Summary

Acts upstream of or within determination of left/right symmetry and heart development. Is active in cytosol. Is expressed in brain; nasal cavity respiratory epithelium; and respiratory system epithelium. Used to study Kartagener syndrome; primary ciliary dyskinesia 21; and visceral heterotaxy. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 21. Orthologous to human DRC1 (dynein regulatory complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Drc1 Products (1)

mRNA Protein Name
NM_001033460.4 NP_001028632.1 dynein regulatory complex protein 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within axoneme assembly IMP
IMP: Inferred from mutant phenotype
34169321 MGI
acts upstream of or within cilium organization IMP
IMP: Inferred from mutant phenotype
34169321 MGI
acts upstream of or within cilium-dependent cell motility IMP
IMP: Inferred from mutant phenotype
34169321 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within protein-containing complex assembly IMP
IMP: Inferred from mutant phenotype
34169321 MGI
acts upstream of or within single fertilization IMP
IMP: Inferred from mutant phenotype
34169321 MGI
acts upstream of or within sperm flagellum assembly IMP
IMP: Inferred from mutant phenotype
34169321 MGI
Cellular Component GO Annotation Evidence References Source
is active in cilium IMP
IMP: Inferred from mutant phenotype
34169321 MGI
is active in cytosol IDA
IDA: Inferred from direct assay
27914912 MGI
is active in sperm flagellum IMP
IMP: Inferred from mutant phenotype
34169321 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynein regulatory complex protein 1

  • coiled-coil domain containing 164

  • coiled-coil domain-containing protein 164

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03192 CRNN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03991 DRC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20719 Drc1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27230 Drc1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Drc1 NCBI NCBI:92749